20 tests/kit
- Contain dithiothreitol lysis solution and Wright staining solution
- Easy identification: sperm with fragmented DNA does not show a dispersion halo or the halo is minimal
- 20 tests/kit, stable for 12 months at 2-8℃
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The CARIAD Sperm DNA Fragmentation Kit employs the Sperm Chromatin Diffusion (SCD) method to assess sperm DNA integrity, crucial for male fertility. Sperm DNA fragmentation (SDF) indicates the presence of sperm with damaged DNA, affecting fertility and reproductive outcomes. This kit is based on the observation that sperm with fragmented DNA do not show the typical halo of dispersed DNA loops seen in sperm with intact DNA, after acid denaturation and removal of nuclear proteins. Additionally, the SCD test can be utilized to evaluate sperm DNA longevity, revealing latent DNA damage not immediately apparent during initial assessments. -
CARIAD Modified Papanicolaou Staining Solution is tailored for sperm morphology assessment in semen samples. Utilizing Hematoxylin, eosin, and light green stains, it offers an enhanced staining outcome. Compared to traditional PAP staining, this solution dramatically reduces staining time to just 10 minutes. It remains stable for 6 months when stored between 4-30℃ and retains its effectiveness for 3 months after opening.50mL x 3
- Faster staining than conventional PAP staining, requiring only 10 minutes
- Distinct morphological features after staining
- Stable for 12 months at room temperature
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The CARIAD SEA-5 Seminal Plasma POCT Automated Chemistry Analyzer is an in vitro diagnostic biochemistry instrument tailored for the quantitative determination of Seminal Plasma biomarkers. Recognizing the importance of prompt results in seminal plasma analysis for diagnostic and fertility evaluations, the SEA-5 is designed to provide immediate outcomes. This eliminates the dependence on off-site laboratories and simplifies the process for Andrologists, doing away with intricate manual tests. The device accommodates cartridges that can assess up to five parameters simultaneously, and these cartridges are designed for single-use. Users can navigate the system through its 10-inch touch screen display, and results can be conveniently printed on-site via the built-in thermal printer.Single unit
- 5 parameters in 1 single-test cartridge
- 12 minutes for 5 parameters
- Sample volume: 5-20μL
- 3 steps operation
- Highly accurate results with CV ≤ 3%
- No user calibration necessary
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The CARIAD Sperm Membrane Detection Kit (Hypotonic Dilation Method) facilitates the swift detection of sperm membrane function and vitality. Operating on the principle of the semi-permeability of an intact sperm membrane, this kit offers insights into the fertilization capability to a certain degree. Formulated with 1.35% fructose and 0.74% sodium citrate, it employs a method recommended by the WHO for accurate and reliable results.20 tests/kit
- WHO recommended method
- Ready to use, simple to operate, and easy to count
- Contain 1.35% fructose and 0.74% sodium citrate
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CARIAD Sperm Nuclear Staining Solution (Acridine Orange Method) is specifically formulated for staining sperm nuclei and evaluating the presence of single-stranded DNA in damaged sperm chromatin. Endorsed as a recommended method by the WHO, this solution provides accurate insights into sperm chromatin integrity. When stored at 2-8℃, the solution remains stable and effective for up to 12 months.20 tests/kit
- Faster staining than conventional PAP staining, requiring only 10 minutes
- Distinct morphological features after staining
- Stable for 12 months at room temperature
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CARIAD Sperm Staining Solution, based on the Diff-Quik Method, is designed for sperm morphology staining analysis. This staining solution facilitates the quantitative evaluation of both normal and abnormal sperm forms within an ejaculate. Incorporating eosinophilic xanthene and basophilic thiazine stains, it is particularly suitable for CASA (Computer-Assisted Sperm Analysis). With a shelf life of 12 months at room temperature, this method is endorsed by the WHO for swift semen staining procedures.3 x 100mL
- WHO recommended method
- Simple operation and fast results within 5 minutes, competitive when a rapid report is required
- Eosinophilic xanthene and basophilic thiazine stains
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The CARIAD Sperm Vitality Staining Solution utilizes the eosin-nigrosin stain method for swift detection of sperm vitality. Dead sperm cells absorb the eosin, resulting in a red stain due to their altered membrane permeability. In contrast, live sperm with intact cell structures remain unstained. The nigrosin provides a black background, enhancing the distinction between live and dead sperm, making observations more straightforward. This ready-to-use solution offers a simple, one-step staining process.40 tests / kit
- WHO recommended method
- Ready to use, one-step staining technique
- Easy to evaluate with black background: dead sperm’s head is red, live sperm’s head is white or pink after staining
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The CARIAD Staining Solution for the Maturity of Spermatozoan Nucleoprotein (Aniline Blue-Eosin Staining) is designed to evaluate sperm maturity. Through the staining of sperm nucleoprotein, it aids in assessing the occurrence of nucleoprotein transition. Upon application, immature sperm heads are distinctly colored blue, while mature sperm heads appear red, simplifying evaluations. Aniline blue serves as a standard test to determine chromatin condensation in sperm DNA. The solution remains stable for up to 12 months when stored at 2-8℃, and maintains its efficacy for 15 days at 2-8℃ after being opened.40 tests/kit
- WHO-recommended method
- Aniline blue and eosin Y stains
- Easy to evaluate: immature sperm head is blue and mature sperm head is red after staining
- Stable for 12 months at 2-8℃ and 15 days at 2-8°C after opening
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The CBS Digitcool® series provides a versatile array of controlled-rate freezers catering to diverse cryopreservation requirements. The line includes:- Digitcool®: A robust solution for large cryopreservation centers, accommodating high-security straws, cryogenic vials, glass ampoules, and blood bags, with custom rack options available.
- Mini-Digitcool®: Tailored for users with moderate freezing needs, such as tissue banks and cellular therapy centers, it supports a variety of storage formats including straws, tubes, and bags.
- Micro-Digitcool®: A compact freezer preferred by tissue and cord blood banks, cellular culture facilities, and clinical trials, offering efficient storage for straws, tubes, and bags.
- Nano-Digitcool®: Designed for daily use in Assisted Reproductive Technology centers, this compact freezer is ideal for smaller-scale, yet critical, cryopreservation needs. Each unit in the Digitcool® line is meticulously crafted to ensure reliability, consistency, and performance for the critical task of biological sample preservation.
Single unit
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Cryo Bio System™ (CBS) Goblets and Visotubes maximize your cryotank’s limited space by offering a unique spatial and colour-coded organization system for storing biological samples.5 goblets/pkg or 10 visotubes/pkg
- Goblets and Visotubes come in a variety of colours, shapes and sizes, allowing for easy sample identification
- Goblets hold 12 Visotubes and can hold a maximum of 168 CBS High Security Vitrification Straws, or 240 CBS High Security 0.3 ml or 0.5 ml Straws
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The CBS™ High Security Sperm Straw with braided plug is designed for the cryopreservation of human sperm. Made from a transparent ionomeric resin that is biocompatible and chemically inert, the straw’s high surface to volume ratio provides improved and homogenous heat exchange over the total volume of the straw. Available in two sizes, High Security Sperm Straws are designed for use with SYMS-type sealers. This fully closed vitrification system eliminates any possibility of cross-contamination to the specimen or its environment.20 or 100 straws (packaged in blisters of 5)
- High security closed system vitrification device
- CBS™ 0.3 ml straw features two compartments separated by a white plug: 1) compartment containing semen with a capacity of 0.3 ml, and 2) compartment that accommodates the coloured identification rod and is used for holding when handling liquid nitrogen
- CBS™ 0.5 ml straw features the same technical specifications as the 0.3 ml straw, but has a capacity of 0.5 ml and boasts a coloured external plug surface
- For large-scale application (for example, sperm banks), straws are filled with PACE, MAPI or DIVA automated filling and sealing machines
- Sealing straws with a CBS SYMS sealer ensures an impervious and high security seal
- Leak-proof and shatter-proof, guaranteed all the way down to LN2 temperatures
- Mechanically resistant to pressures of up to 150 kg/cm2 and indestructible under normal conditions of use
- Compatible with all nitrogen freezers and containers, both liquid and vapor phase as well as ultra-low temperature mechanical freezers
- Requires a sterile filling nozzle and a micro-aspirator or a syringe equipped with a special connector are used to manually fill straws
- CE-marked medical device and FDA 510 (k) approved
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The CBS™ High Security Embryo and Sperm Straw with braided plug is designed for the long-term cryopreservation of human sperm and embryos. Made from a transparent ionomeric resin that is biocompatible and chemically inert, these high-quality straws have a high surface to volume ratio for improved and homogenous heat exchange over the total volume of the straw. The fully closed vitrification system eliminates any possibility of cross-contamination to the specimen or its environment.20 straws (4 packs of 5 blisters each)
- High security closed system vitrification device
- Straws have two distinct compartments separated by the braided plug that allows for controlled loading and extracting
- Tamper-proof top compartment for placement of a coloured identification rod to guarantee sample traceability
- Leak-proof and shatter-proof, guaranteed all the way down to LN2 temperatures
- Mechanically resistant to pressures of up to 150 kg/cm2 and indestructible under normal conditions of use
- Sealing straws with a CBS™ SYMS sealer assures an impervious and high security seal
- Compatible with all nitrogen freezers and containers, both liquid and vapor phase as well as ultra-low temperature mechanical freezers
- Requires a sterile filling nozzle and a micro-aspirator or a syringe equipped with a special connector are used to manually fill straws
- CE-marked medical device and FDA 510 (k) approved
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CBS™ High Security Tubes are a unique fully secured system for storage of biological materials in liquid nitrogen. Once sealed, the tube eliminates any concerns related to cross-contamination and sample degradation from oxidation and evaporation. The High Security resin material is compatible with cryogenic storage temperatures from -80°C to LN2. The tubes are designed to function with the CBS™ SYMS III Sealer.20 sterile tubes
- High security closed system vitrification device
- Ideal for the cryopreservation of biological samples: biobanking; preservation of fertility (ovarian and testicular tissue, and sperm); biological tissue for clinical phase or research; biological samples for blood banks and blood transfusion centers; cell and genetic therapy (clinical phase and therapeutic applications); and the packaging of vaccines and heat-sensitive drugs
- Validated as leak-proof and shatter-proof in all cryogenic temperatures including temperatures as low as LN2 liquid phase
- Indestructible under normal conditions of use
- Traceable with coloured inserts, 2D data matrix coded inserts, and compatible with cryoresistant labels
- Compatible with cryogenic storage temperatures from -80°C to LN2
- Compatible with common storage systems, manual and automatic filling systems, programmable freezers and liquid nitrogen, vapor phase and mechanical freezers
- CE-marked medical device with Class II/a certification, appropriate for clinical phase trials and therapeutic applications
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CBS™ High Security Vitrification (HSV) Straws are designed for the vitrification of human oocytes and embryos (all stages). The straw is made from transparent biocompatible ionomeric resin, making it secure, durable, and simple to use. The physical properties and method of sealing HSV straws guarantees that they remain sealed when immersed and stored in liquid nitrogen. The fully closed vitrification system eliminates any possibility of cross-contamination.4 individual peel-off blisters / pack
- High security closed system vitrification device
- Composed of three distinct parts: a High Security ultra-thin outer straw, featuring a pre-sealed weighted end and flared opening; a capillary tube with pre-formed, fully clear gutter co-injected with its coloured identification rod; and a blue introduction device
- One-step opening and retrieval
- Designed for use with CBS™ SYMS Sealers for perfect sealing, and fully compatible with CBS™ storage products
- Packaging designed to provide a "double sterile barrier", facilitating transfers into aseptic working areas
- Compatible with all nitrogen freezers and containers, both liquid and vapor phase, as well as ultra-low temperature mechanical freezers
- International Standards Compliance CE, FDA 510 (k) cleared
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CBS™ ID Jackets are designed for use with CBS™ 0.5 ml High Security Sperm Straws. These external identification sleeves can be identified with the application of a custom label or written on directly with a cryo-safe marker. ID Jackets become secure once the straw is sealed for reliable tracking of straws in long-term storage.50 jackets / pkg
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The CBS™ Micro-aspirator device is used for manually filling straws during cryopreservation. It eliminates the risk of contamination and is compatible with all CBS™ straws.Single device
- Eliminates risk of contamination while filling straws
- Compatible with all CBS™ straws
- No specific maintenance required
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The Cryo Bio System™ (CBS) SYMS I Sealer is a tabletop device specifically designed to seal CBS High Security straws. Crafted with ionomeric resin, this sealer is highly reliable and durable, requiring minimal maintenance and ensuring optimal operation in the long run. The SYMS I can effectively seal 0.3 ml and 0.5 ml CBS High Security straws, as well as CBS High Security Vitrification straws. These straws are integral components of the CBS closed cryopreservation system, and the SYMS I Sealer ensures a secure seal, contributing to the system's overall safety and effectiveness. The sealer provides users with flexibility in operation, as it can be activated by either a push-button or a foot switch, depending on the user's preference. This user-friendly functionality makes the SYMS I Sealer a valuable asset in laboratories and facilities that use the CBS cryopreservation system.Single unit
- Two options to best suit your workflow: push-button or foot switch
- Requires only 5 minutes per day for start-up, maintenance, and shut-down procedures
- Easily cleaned with ethanol or a non-corrosive decontaminant fluid
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The Cryo Bio System™ (CBS) SYMS III Sealer is a bench top unit designed to thermally seal all CBS™ High Security products, including CBS™ High Security 0.3 ml, 0.5 ml and 2 ml straws, CBS™ High Security Tubes, and CBS™ High Security Vitrification straws. Using an automatic detection system, the unit uses pre-set specific combinations of seal temperatures, time and jaw positions for each CBS device. Due to its compact size, the SYMS III can be used in a variety of locations, including on the lab bench, under laminar flow, or even in field operations.Single unit
- Multilingual interface (French, English, Spanish and Chinese) + 4 optional languages
- Laboratory glove-compatible colour touch screen
- Machine cycle display: pre-heating, ready status and sealing in progress
- Two sealing modes: automatic detection or operator-controlled via the touch screen
- Fault signal with messages and alarms
- Display and tracking of maintenance modes
- Easy to clean and service
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CBS™ Weighted ID Rods are designed for use with CBS™ 0.3 ml High Security Sperm Straws. Thee rods provide internal colour-coding for easy sample identification, and are weighted to prevent filled straws from floating when immersed in liquid nitrogen.10 rods / pkg
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CELL-VU® Pre-stained Morphology slides provide clean and clear slides for rapid cellular visualization and differential cell assessment. Each slide contains a dried layer of stain that facilitates morphology assessment when in contact with cells. Samples are applied directly to the slide and a coverslip placed over the sample, reducing exposure to harmful external variables. CELL-VU® slides combine conventional microscope slides with a proprietary combination of methylene blue and cresyl violet stains into a single, ready-to-use device.75 slides/box
- Used for the staining spermatozoa, blood, CSF, and urine for cytology
- Disposable, reducing clinician’s unnecessary exposure to bodily fluids
- One step process limits exposure to reagents and potentially harmful stains
- Highly accurate results
- Increases lab effectiveness by eliminating the need for cleaning
- Used for World Health Organization and Kruger strict morphology sperm assessment from undiluted semen
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CellVision® slides are manufactured from cleaned coated non-toxic glass. Each disposable slide comes with or without an etched grid, has 2 or 4 separate counting chambers, as well as a fixed coverslip with 10, 12, 20 or 100 microns’ depth. The combination of specific chamber-depths and several built-in grid formats facilitate sperm motility assessments and contribute to accurate and reproducible semen analysis. Suitable for a variety of different human and veterinary applications, CellVision® slides eliminate time-consuming cleaning procedures and reduce the risk of exposure to infectious material.25 slides / box
- Disposable
- Made from cleaned and coated non-toxic glass
- Available in 2 and 4 chambers formats with 10 to 100 μm fixed-depth coverslips
- Colour-coded by format
- Slides come with an identical image, dimensions and fitted counting grid as a re-usable hematocytometer
- For use in human and veterinary semen analysis
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The Makler Sperm Counting Chamber is designed for accurate sperm count analysis directly from an undiluted semen specimen, commonly used during IVF and andrology procedures. This chamber is distinguished by its 10-micron depth, which prevents blurring and allows sperm to move freely at a single focal plane for observation. A replacement coverslip grid is available in case the original that comes with the unit is damaged. The chamber requires a 20X objective or 20X eyepieces for proper usage.- A built-in grid on the cover glass, enhancing ease of use by eliminating the need for inserting and removing grids in the microscope eyepiece.
- Reusability, with easy cleaning using a non-bleach disinfectant solution.
- Self-controlled accuracy test visible through color fringes at the four contact points, ensuring the cover glass remains unaffected by the applied sample.
- Dependable repeated use without the need for recalibration.
- Precision manufactured and individually checked with a laser beam to ensure accuracy.
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The ColdStash VitroStash 47L Dewar is an innovative storage solution developed to optimize capacity in laboratory settings. The VitroStash is equipped with twelve stacked canisters, which effectively doubles the storage capacity when compared to traditional canister systems. Created specifically for IVF clinics, the VitroStash system accommodates up to 384 patients without necessitating any operational changes in the lab. The VitroStash system not only aids in addressing storage limitations but also reduces costs by eliminating the need for additional Dewars, alarms, monitors, and by lowering LN2 consumption. Thus, it serves as an economical and user-friendly solution for labs.Single unit
- A dewar retrofit with VitroStash will cost about half of a new dewar.
- VitroStash increases current storage capacities by 2X.
- No need to change current lab configurations.
- Enhanced grid configuration allows for simple, ergonomic storage.
- Fewer dewars further reduces energy and LN2 costs.
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The VitroStash Max Dewar is a 95-liter high-capacity storage solution for laboratories, delivering a significant increase in storage capability while maintaining operational efficiency. This model comes equipped with twelve VitroStash stacked canisters, canes, and goblets, all designed for maximized storage density. The VitroStash Max Dewar stands out for its economic benefits, notably reducing per patient storage and operating costs compared to large LN2 freezers. It is engineered for lower liquid nitrogen and energy usage, contributing to sustainable operation. Enhancing lab safety, it minimizes alarm occurrences, thus reducing potential risks and demands on staff. With its ample storage capacity, compact footprint, and cost-saving features, the VitroStash Max Dewar offers an effective storage solution for labs.Single unit
- Made of high-strength aluminum alloy
- Advanced powder coat finish for increased durability
- A locked-lid switch for safety of preserved sample is optional
- Service life is five years
- Temperature and Liquid Level monitor available